MHC

MHC may refer to:

Biology

• Major histocompatibility complex, a highly polymorphic region on chromosome 6 with genes particularly involved in immune functions
• Myosin heavy chain, part of the motor protein myosin's quaternary protein structure

Colleges

• Mars Hill College (now Mars Hill University), a college in Mars Hill, North Carolina, USA
• Mount Holyoke College, a college in South Hadley, Massachusetts, USA
• William E. Macaulay Honors College, an honors college within the City University of New York

Health

• Managed health care
• Mental health counselor
• Metropolitan Hospital Center, East Harlem, New York City

Sports

• Malaysian Hockey Confederation
• Mediterranean Handball Confederation
• Mid Hudson Conference
• Milwaukee Hurling Club

Other

• Maimonides Heritage Center
• Massachusetts Historical Commission
• Mile high club
• Mochoʼ language (ISO 639:mhc), a moribund Mayan language spoken in Chiapas, Mexico
• Mocopulli Airport (IATA: MHC), Dalcahue, Los Lagos, Chile
• Model of hierarchical complexity
• Mohawk–Hudson convergence, a meteorological phenomenon
• Murphy-Hoffman Company
• Museum of the History of Catalonia
• A US Navy hull classification symbol: Coastal minehunter (MHC)