Beclometasone/formoterol

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Beclometasone/formoterol
Combination of
Beclometasone dipropionateGlucocorticoid
Formoterol fumarateLong-acting β2 agonist
Names
Trade namesFostair; Fostair Nexthaler; Luforbec, others
Other namesBeclometasone/eformoterol[1]
Clinical data
Main usesAsthma, chronic obstructive pulmonary disease (COPD)[2]
Side effectsPneumonia, thrush, allergic reactions, low potassium, headache, glaucoma, blurry vision[2]
Routes of
use
Inhalation
Typical dose1 to 2 puffs BID[2]
External links
AHFS/Drugs.comInternational Drug Names
Legal
Legal status

Beclometasone/formoterol, sold under the brand name Fostair, is a combination medication used to treat asthma and chronic obstructive pulmonary disease (COPD).[2] In asthma it may be used both as long-term prevention and for sudden worsening.[5] It is a second line treatment.[2] It is used by breathing the medication in.[2]

Side effects are those of the two medications it contains.[2] These may include pneumonia, thrush, allergic reactions, low potassium, headache, glaucoma, and blurry vision.[2] Safety in pregnancy is unclear.[2] It contains beclometasone dipropionate, a corticosteroid; and formoterol fumarate dihydrate a long-acting β2 agonist (LABA).[2]

The combination was approved for medical use in the United Kingdom in 2007, and Australia in 2020.[2][1][6] It is on the World Health Organization's List of Essential Medicines as an alternative to budesonide/formoterol.[7] In the United Kingdom 120 doses costs the NHS about £30 as of 2023.[5]

Medical use

Dosage

It is often used as one to two puffs twice per day.[2] Up to 8 doses per day may be used.[5]

References

  1. 1.0 1.1 "Australian Product Information - Fostair 100/6 (Beclometasone dipropionate and formoterol (eformoterol) fumarate dihydrate) pressurised inhalation solution". Therapeutic Goods Administration (TGA). April 2020. Archived from the original on 20 January 2021. Retrieved 22 September 2020.
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 "Fostair 100/6 micrograms per actuation pressurised inhalation solution - Summary of Product Characteristics (SmPC)". (emc). 3 March 2020. Archived from the original on 19 July 2020. Retrieved 18 July 2020.
  3. "Fostair 200/6 micrograms per actuation pressurised inhalation solution - Summary of Product Characteristics (SmPC)". (emc). 13 February 2019. Archived from the original on 19 July 2020. Retrieved 18 July 2020.
  4. "Fostair NEXThaler 200 micrograms/6 micrograms per actuation inhalation powder - Summary of Product Characteristics (SmPC)". (emc). 16 April 2019. Archived from the original on 19 July 2020. Retrieved 18 July 2020.
  5. 5.0 5.1 5.2 BNF 84 (British National Formulary) September 2022 (84 ed.). Pharmaceutical Press. 2022. p. X. ISBN 978-0857114327.
  6. "AusPAR: Beclometasone dipropionate/formoterol (eformoterol) fumarate dihydrate". Therapeutic Goods Administration (TGA). 3 August 2020. Archived from the original on 1 October 2020. Retrieved 22 September 2020.
  7. World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.

External links

Identifiers: