List of skin conditions associated with internal cancer

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This is a list of skin conditions associated with internal cancer.[1][2] It does not include skin infections associated with cancer or cancers that spread to skin.[2] Some have stronger associations with cancers than others.[3]

Cutaneous conditions associated with internal benign tumors and/or malignancies
Cutaneous condition Internal malignancy Image Notes
Acanthosis nigricans[3]
Acquired ichthyosis[4] Hodgkin disease
Acrokeratosis paraneoplastica Squamous cell carcinoma of the upper respiratory or gastrointestinal tracts
Clubbing of fingers[3] Lung cancer[3]
Dermatomyositis Lung cancer in men, breast and gynaecological tumours in women and colorectal cancers in both sexes
Erythema gyratum repens[5] Lung cancer, breast cancer, oesophageal cancer
Erythroderma and exfoliative dermatitis Mycosis fungoides or Sézary syndrome
Hypertrichosis lanuginosa acquisita Lung cancer
Leser–Trélat sign Gastrointestinal adenocarcinoma
Migratory thrombophlebitis Pancreatic adenocarcinoma
Necrolytic migratory erythema Glucagon secreting pancreatic islet cell adenoma
Paraneoplastic pemphigus Non-Hodgkin lymphoma[nb 1]
Chronic lymphocytic leukemia
Castleman's disease[nb 1]
Sarcoma
Thymoma
Paraneoplastic pigmentation Small cell bronchial carcinoma
Pityriasis rotunda Hepatocellular carcinoma
Porphyria cutanea tarda and variegate porphyrias Hepatocellular Carcinoma
Pyoderma gangrenosum Hematological malignancy
Scleroderma‐like skin changes Carcinoid syndrome
Sweet syndrome Hematological malignancy
Tripe palms[3] Lung cancer, stomach cancer, ovarian cancer[3]
Trousseau sign of malignancy

Footnotes

  1. 1.0 1.1 Non-Hodgkin lymphoma is the most common cause of paraneoplastic pemphigus in adults. Castleman's disease is the most common cause of paraneoplastic pemphigus in children.

See also

References

  1. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "28. Dermal and subcutaneous tumors". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 633–634. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-08. Retrieved 2023-08-07.
  2. 2.0 2.1 Wick, Mark R.; Patterson, James W. (July 2019). "Cutaneous paraneoplastic syndromes". Seminars in Diagnostic Pathology. 36 (4): 211–228. doi:10.1053/j.semdp.2019.01.001. ISSN 0740-2570. PMID 30736994. Archived from the original on 2022-11-21. Retrieved 2023-08-01.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Fonia, Athina; Baran, Robert (2021). "Cutaneous paraneoplastic syndromes with nail involvement". In Lipner, Shari (ed.). Nail Disorders: Diagnosis and Management, An Issue of Dermatologic Clinics. Elsevier. pp. 175–182. ISBN 978-0-323-70924-8. Archived from the original on 2023-08-02. Retrieved 2023-08-01.
  4. James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2020). "27. Genodermatoses and congenital anomalies". Andrews' Diseases of the Skin: Clinical Dermatology (13th ed.). Edinburgh: Elsevier. pp. 563–565. ISBN 978-0-323-54753-6. Archived from the original on 2023-08-05. Retrieved 2023-08-04.
  5. Bolognia, Jean L.; Schaffer, Julie V.; Duncan, Karynne O.; Ko, Christine (2021). "15. Figurate erythemas". Dermatology Essentials (2nd ed.). Elsevier. pp. 142–148. ISBN 978-0-323-70971-2. Archived from the original on 2023-08-08. Retrieved 2023-08-05.