File:Biomedicines-11-01406-g002-550.webp
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Summary
| Description |
English: Figure 2. PD1/PD-L1 interaction and immune-checkpoint inhibitors for cancer treatment. In the absence of immune-checkpoint inhibitors, the binding between PD1 and PD-L1 on T-cells and cancer cells, respectively, prevents the activation of T-cells. In presence of anti-PD1 antibodies (ICIs), the T-cell is activated against cancer cells and promotes their death through different immune-mediated pathways. These may generate immune-mediated adverse events. |
| Date | |
| Source | https://www.mdpi.com/2227-9059/11/5/1406 |
| Author | Marsili, L.; Marcucci, S.; LaPorta, J.; Chirra, M.; Espay, A.J.; Colosimo, C |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 22:59, 14 March 2024 | | 550 × 484 (32 KB) | commons>Ozzie10aaaa | Uploaded a work by Marsili, L.; Marcucci, S.; LaPorta, J.; Chirra, M.; Espay, A.J.; Colosimo, C from https://www.mdpi.com/2227-9059/11/5/1406 with UploadWizard |
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