Multiple fibrous papules of the face

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Multiple fibrous papules of the face
Facial angiofibromas
SpecialtyDermatology
SymptomsSmall red/brown bumps across the cheeks and nose in a butterfly distribution[1]
Usual onsetChildhood[1]
Risk factorsTuberous sclerosis, Birt-Hogg-Dubé syndrome, multiple endocrine neoplasia type 1[1]

Multiple fibrous papules of the face are a type of angiofibroma that present as small red/brown bumps across the cheeks and nose in a butterfly distribution.[1] They typically begin in childhood (generally present between 2–5 years of age).[2]: 195 

It is frequently thought to be acne not responding to treatment.[1] It may be associated with tuberous sclerosis, Birt-Hogg-Dubé syndrome and multiple endocrine neoplasia type 1.[3] Gradually the bumps become more prominent and persist throughout life.[4]

It was previously incorrectly referred to as adenoma sebaceum.[5]

Signs and symptoms

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Macri, Angela; Kwan, Eddie; Tanner, Laura S. (2021). "Cutaneous Angiofibroma". StatPearls. StatPearls Publishing. Archived from the original on 2023-04-27. Retrieved 2023-04-29.
  2. Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. ISBN 1-4160-3185-5.
  3. Mocellin, Simone (2021). "57. Cutaneous angiofibroma". Soft Tissue Tumors: A Practical and Comprehensive Guide to Sarcomas and Benign Neoplasms. Switzerland: Springer Nature. pp. 189–192. ISBN 978-3-030-58709-3. Archived from the original on 2023-05-01. Retrieved 2023-04-30.
  4. "DermIS - Adenoma Sebaceum (information on the diagnosis)". www.dermis.net. Archived from the original on 2018-09-01. Retrieved 2016-01-01.
  5. Paller, Amy S.; Mancini, Anthony J. (2020). "9. Cutaneous tumors and tumor syndromes". Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence (6th ed.). St Louis, Missouri: Elsevier. p. 251. ISBN 978-0-323-54988-2. Archived from the original on 2023-04-29. Retrieved 2023-04-29.