Acute cutaneous lupus erythematosus
| Acute cutaneous lupus erythematosus | |
|---|---|
| Specialty | Dermatology |
Acute cutaneous lupus erythematosus is a cutaneous condition characterized by a bilateral malar rash (also known as a "butterfly rash") and lesions that tend to be transient, and that follow sun exposure.[1] The acute form is distinct from chronic and subacute cutaneous lupus erythematosus, which may have different types of skin lesions.[2] Cutaneous lupus erythematosus is associated with both lupus erythematosus-specific lesions and cutaneous manifestations that are not specific to lupus erythematosus, such as oral ulcers and urticaria.[3] Because of the diagnostic criteria used to diagnose systemic lupus erythematosus, a patient with only cutaneous manifestations may be diagnosed with the systemic form of the disease.[2]
Forms
Acute cutaneous lupus erythematosus can be either localized or generalized.[4]
Localized form
The localized form of the disease is most commonly associated with the malar rash and normally develops in a patient's twenties. The localized form occurs only above the patient's neck and is not associated with rashes in other parts of the body.[4]
Generalized form
Generalized acute cutaneous lupus erythematosus includes skin below the patient's neck and is described as a macropapular rash or photosensitive lupus dermatitis.[4] Symptoms include similar erythematic lesions as seen in the localized form, but forms a symmetrical rash and can be mistaken for a drug rash.[4]
See also
References
- ^ Rapini RP, Bolognia JL, Jorizzo JL (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ a b Werth VP (June 2005). "Clinical manifestations of cutaneous lupus erythematosus". Autoimmunity Reviews. 4 (5): 296–302. doi:10.1016/j.autrev.2005.01.003. PMID 15990077.
- ^ McCauliffe DP (March 2001). "Cutaneous lupus erythematosus". Seminars in Cutaneous Medicine and Surgery. 20 (1): 14–26. doi:10.1053/sder.2001.23091. PMID 11308132.
- ^ a b c d Okon LG, Werth VP (June 2013). "Cutaneous lupus erythematosus: diagnosis and treatment". Best Practice & Research. Clinical Rheumatology. Systemic Lupus Erythematosus. 27 (3): 391–404. doi:10.1016/j.berh.2013.07.008. PMC 3927537. PMID 24238695.